CONGENITAL, STATIC FAMILIAL OPHTHALMOPLEGIA

Congenital external ophthalmoplegia.

Familial Congenital Heart Disease

GENETIC imbalance, the result of aneuploidy or chromosomal structural rearrangements, is now recognized as a cause of anomalous embryogenesis. In general, the anomalies have been extensive and severe when the chromosomal abnormalities have affected segments lengthy enough to be detected by use of currently available techniques. The purposes of the present study were: (1) to determine the incide...

[Familial congenital heart disease].

Congenital familial megaloblastic anemia.

Two sisters with a previously unreported megaloblastic anemia unassociated with a deficiency of either folic acid or vitamin B12 are described. Deficiencies of these vitamins were ruled out by standard studies. All other previously reported forms of megaloblastic anemia not secondary to a vitamin deficiency, such as orotic aciduria, were also excluded by appropriate studies. Optimal hemoglobin ...

Congenital familial nodal rhythm.

IT HAS BEEN KNOWN for years that the more serious cardiac arrhythmias, atrial fibrillatiol, atrial flutter,1 and even ventrieular tachyeardia,2 can exist in persons withouLt demonstrable evidence of heart disease. One of the initial comprehensive reviews of this phenomen-on was that of Orgain, Wolff, aind White1 in 1936, who reported 47 individuals presentinig uncomplicated atrial fibrillation ...